A NEW PARADIGM FOR THE REGULATION OF A40926B0 BIOSYNTHESIS

A new paradigm for the regulation of A40926B0 biosynthesis

Dalbavancin is a novel glycopeptide antibiotic with activity against a broad range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA).A40926B0 is the direct precursor of dalbavancin, but the regulatory mechanisms underlying its biosynthesis are not well understood.Additionally, the presence of seven homologs lea

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Elite dan Birokrasi Pemerintahan di Indonesia

In the new Order era, the government had notoriously created a very centralistic and mechanistic bureaucracy consisting of copyright autonomy from central down to the local bureaucracy.On the other side, Indonesian culture with its paternalistic pattern has been a fertile domain for primordialism in the bureaucracy.This condition are conducive for

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The Human dsRNA binding protein PACT is unable to functionally substitute for the Drosophila dsRNA binding protein R2D2 [v1; ref status: indexed, http://f1000r.es/201]

The primary function of the dsRNA binding protein (dsRBP) PACT/RAX is to activate the dsRNA dependent protein kinase PKR in response to stress signals.Additionally, it has been identified as a component of the small RNA processing pathway.A role for PACT/RAX in this pathway represents an important interplay between two modes of post-transcriptional

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